Canvassing for Opinion - aka "Blairs Brain on Cannabis"

IMHO prohibition sentiment requires inherent addiction to status quo, an incapacity to visualise beyond the here and now and a desperate desire to know others might feel the same... Reform is not revolutionary, rather it is evolutionary. Having survived banging your head against a brick wall the evolutionist relishes having stopped. / Blair

Wednesday, October 20, 2004

It's mode of use - stupid!

It's mode of use - stupid!

"smoked marihuana more effective than oral synthetic THC and roughly as safe."

extract - http://www.taima.org/en/grinspoon.htm

Since 1985, oncologists in the U.S. have been legally permitted to administer synthetic THC (the active ingredient in marihuana) orally in capsule form. The trade name is "Marinol". However, it is apparent that inhaled cannabis maybe preferable for a number of reasons. Oral THC is absorbed erratically and slowly into the bloodstream. Furthermore, a patient who is severely nauseated and constantly vomiting may find it almost impossible to keep the capsule digested until it activates. In addition, the effectiveness of THC is dependent on how much is absorbed into the blood stream; investigators have shown that smoked THC is absorbed more effectively. Most patients also prefer smoking marihuana to taking THC orally, as the latter makes them anxious and uncomfortable. One reason that the oral ingestion of THC makes patients anxious and uncomfortable is the difficulty of titrating the dose of oral THC to control the amount that reaches the blood and brain. In 1990, a survey of over 2,000 members of the American Society of Clinical Oncology found that only 43% were satisfied that the available legal anti-emetic drugs (including oral THC) provided adequate relief to all or most of their patients. On average, they considered smoked marihuana more effective than oral synthetic THC and roughly as safe.

SWORN BEFORE ME
at the City of Boston
in the Commonwealth of Massachusetts, USA
this 26th day
of March, 1997

DR. LESTER GRINSPOON


 Blai Anderson
50 Wainoni Road, WAINONI
Christchurch, NZ 8006
phone ++64 3 389-4065   cell 025 2657219

Mild Green Initiatives for your liberty, pleasure, health and safety.

homepage  http://mildgreens.com
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