Canvassing for Opinion - aka "Blairs Brain on Cannabis"

IMHO prohibition sentiment requires inherent addiction to status quo, an incapacity to visualise beyond the here and now and a desperate desire to know others might feel the same... Reform is not revolutionary, rather it is evolutionary. Having survived banging your head against a brick wall the evolutionist relishes having stopped. / Blair

Monday, November 14, 2005

Whole Cannabis and Arthritis

GW Pharma: Sativex explored for use in arthritis - Pharmaceutical Business Review: "Sativex uses two key components from a cannabis plant, Tetrahydrocannabinol and cannabidiol, both of which have been shown to have anti-inflammatory properties. In the small, five-week randomized study, the cannabis-based drug produced statistically significant improvements in pain of movement, pain at rest, quality of sleep, and disease activity.

GW Pharma claims that Sativex may also slow disease progression, although key factors that assess facets such as joint space narrowing have not been reported. Nevertheless, with such promising results, GW Pharma will now look towards the initiation of a larger trial to consolidate its findings.

Unless GW Pharma can prove a slow in disease progression it is unlikely that Sativex will be used as a disease modifying anti-rheumatic drug (DMARD) but as a pain killer. Therefore instead of competing with novel DMARD products in the EU, the drug is likely to be competing with established NSAID painkillers such as diclofenac often used in both rheumatoid and osteoarthritis sufferers. It could also be an alternative to the controversial COX-2 inhibitors of which only Celebrex and Arcoxia are still available in the EU after the withdrawals of Vioxx and Bextra due to cardiovascular side-effects."

also see Big Pharma vs Grannies Special Tea!
�a serious public health issue�
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