Canvassing for Opinion - aka "Blairs Brain on Cannabis"

IMHO prohibition sentiment requires inherent addiction to status quo, an incapacity to visualise beyond the here and now and a desperate desire to know others might feel the same... Reform is not revolutionary, rather it is evolutionary. Having survived banging your head against a brick wall the evolutionist relishes having stopped. / Blair

Monday, December 18, 2006

Its the Fugacity, Stupid!

Daily Mail, UK
Dear Sir/Madam
Re the article by Jenny Hope 16 Dec 2006
'Not only does the tar in a cannabis cigarette contain many of the same
carcinogens as tobacco smoke, but the concentrations of these are up to
50 per cent higher in the smoke of a cannabis cigarette,' it says.

Benzyprene, found in the tar of cannabis joints, can change the make-up
of one of the genes which suppresses tumours and could therefore make
cancer more likely for people who smoke joints.

There are also more than 75 case studies of young cannabis smokers with
cancers of the throat and gullet - diseases usually rare in people under
60.

Among the many erroneous claims asserted most all of which fails to account for current policy and how it's perverse application may help or hinder the concerns raised (where does anyone get appropriate cancer help from a policeman?)
I take umbrage with and seek correction's to be made 'in the interest of public good' for the egregious obfuscations related to cancer, cannabis and (ingested) air-pollution.
Tobacco Documents Online ( Oak Ridge Natl Lab Toxicology + Industrial Health ) says about Benzo-a-pyrene [BaP]
  • The food chain is the dominant pathway of human exposure, accounting for about 97% of the total daily in- take of BaP. Inhalation and consumption of contaminated water are only minor pathways of human exposure.
  • The long-term average daily intake of BaP by the general population of the U.S. is estimated to be 2.2 micrograms (~g) per day.
  • Cigarette smoking and indoor activities do not substantially increase human exposure to BaP relative to exposures to background levels of BaP present in the environment.
  • Since the increased lifetime risk associated with human exposure to background levels of BaP is 3.5 × 10-4, we conclude that ingestion of food items contaminated with BaP may pose a serious health threat to the U.S. population.
*Research was sponsored by the U.S. Environmental Protection Agency under lnteragency Agreements
U.S. Department of Energy. Toxicology and Industrial Health, 7:3, p. 141-I57

The combustion of fossil fuels is the primary anthropogenic source of background levels of polycyclic aromatic hydrocarbons (PAHs) present in the environment (Archer et at., 1979; Edwards, 1983). While there is no known intentional production or use of the most toxic PAH, benzo-a-pyrene (BaP), it has been detected in virtually all environmental media and food items consumed by animals and humans - environmental contamination of BaP is widespread. environmental behavior of organic chemicals chronically released into the environment Because BaP is a potential human carcinogen, the environmental fate and accumulation of this compound in the food chain is of particular concern.
Its the Fugacity, Stupid.
Its all in the environmental behavior and that BaP's are chronically released into the environment

Fugacity Food Chain (FFC) models estimate the concentration of [complex organic] chemicals in air, water, soil, bottom and suspended sediments and aquatic biota (fish). Using these concentrations we can predict the amount of a chemical that accumulates in the food chain and the average daily intake by the general population.

Using FCC helps predict the health impact of BaP in people by monitoring:
1) its physicochemical properties;
2) its bioaccumulation potential in living organisms;
3) degradation rates for processes that remove the compound from the system; and
4) an estimate of emissions into air, water, and soil. The physicochemical properties of BaP and its bioconcentration and biotransfer factors.

BaP released into the atmosphere may remain in the vapor phase or may sorb onto particulates.

Deposition of BaP onto outer plant surfaces contributes substantially to vegetative contamination.

Organics that have accumulated on outer plant surfaces have a typical weathering half-life of 14 days and chronically constantly replaced. (see also: The Report on Diesel Exhaust, Activity of Particulate Organic Matter and other mildgreen analysis on environmental/health from mobile sources )
Finally, I refer your journalist staff to a more balanced analysis on cannabis and cancer from the USA NIDA's Prof Donald Tashkin who after decades of research into cannabis related harms conceded that its use may even have a prophylactic effect in the case of lung cancer. Other recent multidisciplinary studies have found no epidemiological correlation with cannabis/cancer in heavy users (20,000 joints.)
Yours faithfully,
Blair Anderson
http://mildgreens.com
ph (643) 389 4065 cell 027 265 7219
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