Canvassing for Opinion - aka "Blairs Brain on Cannabis"

IMHO prohibition sentiment requires inherent addiction to status quo, an incapacity to visualise beyond the here and now and a desperate desire to know others might feel the same... Reform is not revolutionary, rather it is evolutionary. Having survived banging your head against a brick wall the evolutionist relishes having stopped. / Blair

Tuesday, October 02, 2007

Caffeine withdrawal = Psychiatric disorder

(WebMD) Researchers are saying that caffeine withdrawal should now be classified as a psychiatric disorder.

A new study that analyzes some 170 years' worth of research concludes that caffeine withdrawal is very real — producing enough physical symptoms and a disruption in daily life to classify it as a psychiatric disorder. Researchers are suggesting that caffeine withdrawal should be included in the next edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM), considered the bible of mental disorders. "I don't think this means anyone should be worried," says study researcher Roland Griffiths, PhD, professor of psychiatry and neuroscience at Johns Hopkins School of Medicine.

CaffeineImage via Wikipedia

"What it means is that the phenomenon of caffeine withdrawal is real and that when people don't get their usual dose, they can suffer a range of withdrawal symptoms."

His research, published in the October issue of Psychopharmacology, analyzes 66 previous studies on the effects of caffeine withdrawal. One Coffee Sets the Stage Griffiths' analysis shows as little as one cup of coffee can cause an addiction, and withdrawal from caffeine produces any of five clusters of symptoms in some people:
  • Headache, the most common symptom, which affects at least of 50 percent of people in

    Magnetic Resonance Imaging scan of a headImage via Wikipedia

    caffeine withdrawal

  • Fatigue or drowsiness

  • "Unhappy" mood, depression, or irritability

  • Difficulty concentrating

  • Flu-like symptoms such as nausea, vomiting, muscle pain, and stiffness."

Onset of these symptoms typically occurs within 12 to 24 hours of stopping caffeine and peaks one to two days after stopping," Griffiths tells WebMD. "The duration is between two and nine days."

A new revelation in Griffith's analysis may be what upgrades caffeine withdrawal from its current "more study is needed" status to "disorder" status: These withdrawal symptoms are severe enough in about one in eight people to interfere with their ability to function on a day-to-day basis.

"The withdrawal symptoms can be mild or severe, but it's estimated that 13 percent of people develop symptoms so significant that they can't do what they normally would do — they can't work, they can't leave the house, they can't function," he says.

Interference, Not Just Symptoms

That's key for inclusion in the DSM, says John Hughes, MD, a University of Vermont psychiatrist and addiction specialist who serves as a medical consultant for the book. "Caffeine withdrawal was proposed for DSM-IV [the current edition of DSM], but the major objection to including it as a disorder was an absence of good data showing clinical significance," says Hughes, who was not involved in Griffiths' study. "Not only do you have to show it produces symptoms, but you have to show that those symptoms can interfere with daily function."

Caffeine's principal mode of action is as an a...Image via Wikipedia

This study, co-authored by American University researcher Laura Juliano, PhD, does that, says Hughes. "It shows very nicely that the effects of caffeine withdrawal are consistent, that several symptoms are of large magnitude, and that a minority of people cannot perform daily functions when they go without caffeine," he tells WebMD.

Their study shows no difference in withdrawal symptoms based on the source of caffeine, which includes coffee and sodas, some teas, chocolate, and medications such as Excedrin and NoDoz.

"Caffeine is caffeine, from a pharmacologic point of view," says Griffiths.

In the U.S., average daily caffeine intake is about 280 milligrams — what's in two mugs of coffee or three to five cans of soft drinks. Up to 90 percent of people regularly use caffeine, and about 100 milligrams is enough to trigger withdrawal symptoms, says Griffiths.

Chemical structure of Caffeine and the three p...Image via Wikipedia

Should You Quit? Still, both experts say just because caffeine withdrawal can produce symptoms doesn't mean it's dangerous. "I'm hesitant to even call caffeine an 'addiction,' because addiction has to do with the inability to stop or control," says Hughes. "Most people can stop drinking coffee, even if they have symptoms when they do." Griffiths agrees. "The fact that caffeine produces physical dependence isn't necessarily grounds in and of itself to quit," he says.

"But if you want to, the best way is with a gradual withdrawal — just slowly change the proportion of caffeinated and decaffeinated coffee until you're only drinking decaf. Don't stop abruptly; that will likely cause more symptoms."

The real message of Griffiths' findings: "It's that people should realize the possibility that caffeine withdrawal may be responsible for some symptoms," says Hughes. "If you have recurring headaches or fatigue, you really to think that it may be due to caffeine withdrawal."

Juliano, L. Psychopharmacology, October 2004.
Roland Griffiths, PhD, professor of psychiatry and neuroscience, Johns Hopkins School of Medicine, Baltimore.
John Hughes, MD, professor, department of psychiatry, psychology and family practice, University of Vermont, Burlington.

also see

Blair Anderson

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  • At 4:17 am, February 12, 2009, Anonymous Anonymous said…

    Caffeine Addiction - Caffeine Effects and Withdrawal part II

    Caffeine addiction shows up when a person cannot stop consuming caffeine in high amounts, causing his/her body to demand the substance and react negatively if that no caffeine is intake. Caffeine may not be addictive in the traditional sense, but the body builds up a tolerance over time; some people find it very hard to function well without at least one cup of strong coffee or tea in the morning. The stimulating effects of caffeine are caused by a central nervous reaction, the heart rate increases, blood vessels expand and the brain receives more oxygen. These caffeine effects can last for up to 8 hours, and once they go off then the body feels extremely lazy and slow as a side effect.

    Caffeine addiction can even cause death, mainly because the abuse of any stimulant can cause high blood pressure or and heart problems, so if you abuse of it chances are you put yourself at the highest risk of a heart attack.

    You need to be careful with caffeine withdrawal because it affects your overall health and therefore, you need to control your consumption of caffeinated products to prevent your body reactions to caffeine withdrawals. If you need more information about caffeine effects and caffeine addiction symptoms or prevention, please investigate a little further on this topics.

    You can find more info at:


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